Denny Hamlin won the Cook Out Southern 500 NASCAR Cup Series race at Darlington Raceway. The win is his 1st win of the year, 4th win at Darlington and 45th career win.

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Stage 1 was won by Denny Hamlin. Stage 2 was won by Kyle Larson.

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There were 18 lead changes among 10 drivers and 11 cautions for 52 yellow flag laps.